Home

Truncheon leča Poudarek atomic basis of crm1 cargo recognition release and inhibition cilj temperatura Zaviti

Cells | Free Full-Text | Structural Basis of Targeting the Exportin CRM1 in Cancer
Cells | Free Full-Text | Structural Basis of Targeting the Exportin CRM1 in Cancer

Chromosome Region Maintenance 1 (XPO1/CRM1) as an Anticancer Target and Discovery of Its Inhibitor | Journal of Medicinal Chemistry
Chromosome Region Maintenance 1 (XPO1/CRM1) as an Anticancer Target and Discovery of Its Inhibitor | Journal of Medicinal Chemistry

Discovery and biological evaluation of a small‐molecule inhibitor of CRM1 that suppresses the growth of triple‐negative breast cancer cells - Gao - 2021 - Traffic - Wiley Online Library
Discovery and biological evaluation of a small‐molecule inhibitor of CRM1 that suppresses the growth of triple‐negative breast cancer cells - Gao - 2021 - Traffic - Wiley Online Library

Model for cooperative CRM1 export complex assembly and disassembly... | Download Scientific Diagram
Model for cooperative CRM1 export complex assembly and disassembly... | Download Scientific Diagram

A 2.1-Å-Resolution Crystal Structure of Unliganded CRM1 Reveals the Mechanism of Autoinhibition - ScienceDirect
A 2.1-Å-Resolution Crystal Structure of Unliganded CRM1 Reveals the Mechanism of Autoinhibition - ScienceDirect

Selinexor decreases HIF-1α via inhibition of CRM1 in human osteosarcoma and hepatoma cells associated with an increased radiosensitivity | Journal of Cancer Research and Clinical Oncology
Selinexor decreases HIF-1α via inhibition of CRM1 in human osteosarcoma and hepatoma cells associated with an increased radiosensitivity | Journal of Cancer Research and Clinical Oncology

DDC | Free Full-Text | Selinexor and Other Selective Inhibitors of Nuclear Export (SINEs)—A Novel Approach to Target Hematologic Malignancies and Solid Tumors
DDC | Free Full-Text | Selinexor and Other Selective Inhibitors of Nuclear Export (SINEs)—A Novel Approach to Target Hematologic Malignancies and Solid Tumors

Karyopherin-mediated nucleocytoplasmic transport | Nature Reviews Molecular Cell Biology
Karyopherin-mediated nucleocytoplasmic transport | Nature Reviews Molecular Cell Biology

Selective inhibitor of nuclear export - Wikipedia
Selective inhibitor of nuclear export - Wikipedia

Cells | Free Full-Text | Structural Basis of Targeting the Exportin CRM1 in Cancer
Cells | Free Full-Text | Structural Basis of Targeting the Exportin CRM1 in Cancer

Structural basis for leucine-rich nuclear export signal recognition by CRM1 | Nature
Structural basis for leucine-rich nuclear export signal recognition by CRM1 | Nature

Atomic basis of CRM1-cargo recognition, release and inhibition - ScienceDirect
Atomic basis of CRM1-cargo recognition, release and inhibition - ScienceDirect

Hitting a moving target: inhibition of the nuclear export receptor XPO1/CRM1 as a therapeutic approach in cancer
Hitting a moving target: inhibition of the nuclear export receptor XPO1/CRM1 as a therapeutic approach in cancer

PDF] Structural Basis of Targeting the Exportin CRM1 in Cancer | Semantic Scholar
PDF] Structural Basis of Targeting the Exportin CRM1 in Cancer | Semantic Scholar

Frontiers | Small Molecule Inhibitors of CRM1
Frontiers | Small Molecule Inhibitors of CRM1

Discovery and biological evaluation of a small‐molecule inhibitor of CRM1 that suppresses the growth of triple‐negative breast cancer cells - Gao - 2021 - Traffic - Wiley Online Library
Discovery and biological evaluation of a small‐molecule inhibitor of CRM1 that suppresses the growth of triple‐negative breast cancer cells - Gao - 2021 - Traffic - Wiley Online Library

XPO1 - Wikipedia
XPO1 - Wikipedia

The nuclear export protein XPO1 — from biology to targeted therapy | Nature Reviews Clinical Oncology
The nuclear export protein XPO1 — from biology to targeted therapy | Nature Reviews Clinical Oncology

Atomic basis of CRM1-cargo recognition, release and inhibition - ScienceDirect
Atomic basis of CRM1-cargo recognition, release and inhibition - ScienceDirect

Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore. - Abstract - Europe PMC
Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore. - Abstract - Europe PMC

Viruses | Free Full-Text | Verdinexor Targeting of CRM1 is a Promising Therapeutic Approach against RSV and Influenza Viruses
Viruses | Free Full-Text | Verdinexor Targeting of CRM1 is a Promising Therapeutic Approach against RSV and Influenza Viruses

Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation | Molecular Biology of the Cell
Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation | Molecular Biology of the Cell

Cells | Free Full-Text | The Role of Protein Disorder in Nuclear Transport and in Its Subversion by Viruses
Cells | Free Full-Text | The Role of Protein Disorder in Nuclear Transport and in Its Subversion by Viruses

Structural basis for cooperativity of CRM1 export complex formation | PNAS
Structural basis for cooperativity of CRM1 export complex formation | PNAS

Structural determinants of nuclear export signal orientation in binding to exportin CRM1 | eLife
Structural determinants of nuclear export signal orientation in binding to exportin CRM1 | eLife